Ventricular geometry, strain, and rotational mechanics in pulmonary hypertension.

作者: Sarinya Puwanant , Margaret Park , Zoran B. Popović , W. H. Wilson Tang , Samar Farha

DOI: 10.1161/CIRCULATIONAHA.108.844340

关键词:

摘要: Background— We tested the hypothesis that right ventricular (RV) pressure overload affects RV function and further influences left (LV) geometry, which adversely LV twist mechanics segmental function. Methods Results— Echocardiographic images were prospectively acquired in 44 patients (age, 46±12 years; 82% women) with evidence of pulmonary hypertension (estimated artery systolic pressure, 71±23 mm Hg) age- gender-matched healthy subjects. Patients intrinsic diseases excluded. lateral wall longitudinal strain (LS) interventricular septal (IVS) LS reduced group compared control subjects (−15.9±7.6% versus −25.5±6.1%, P<0.001; −17.3±4.4% −20.2±3.9%, P=0.002, respectively), whereas was preserved. IVS LS, but not correlated (r=0.56, P<0.01; r=0.32, P<0.01) eccentricity index (r=0.5...

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