The appearance of 20α-hydroxysteroid dehydrogenase activity in preovulatory follicles of immature rats treated with pregnant mare serum gonadotropin

作者: B. Eckstein , M. Raanan , N. Lerner , S. Cohen , A. Nimrod

DOI: 10.1016/0022-4731(77)90053-X

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摘要: Abstract 20α-Hydroxysteroid dehydrogenase (20α-SDH) activity, believed to be present exclusively in regressing corpora lutea, was demonstrated preovulatory follicles of immature rats exposed 52 h previously pregnant mare serum gonadotropin (PMSG). Production progesterone from 20α-dihydroprogesterone proportional enzyme concentration and time incubation, obeyed Michaelis-Menten kinetics. Induction follicular 20α-SDH activity is not dependent on the LH surge, since same found before after exposure first surge.

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