Expression of Decidual Prolactin-Related Protein in the Rat Decidua*

摘要: It is well established that rat decidual tissue produces a PRL-like hormone(s) binds to the PRL receptor on both corpus luteum and cells initiates profound changes in endocrine milieu required for establishment of pregnancy. The recent cloning PRL-related protein (dPRP) prompted us 1) determine whether expression this gene triggered by decidualization endometrial stromal cells, 2) examine temporal cell-specific pattern its expression, 3) role signals levels messenger RNA (mRNA). Total was isolated from uteri either nonpseudopregnant rats or pseudopregnant with without tissue. A 1-kilobase mRNA species hybridizing strongly dPRP probe present decidualized uteri. No could be detected not subjected decidualization. Developmental studies indicated constant high level until day 1...