Effects of the Consumption of Low-Fat Cooked Ham with Reduced Salt Enriched with Antioxidants on the Improvement of Cardiovascular Health: A Randomized Clinical Trial.

作者: Desiree Victoria-Montesinos , Raul Arcusa , Ana Maria Garcia-Munoz , Silvia Perez-Pinero , Maravillas Sanchez-Macarro

DOI: 10.3390/NU13051480

关键词:

摘要: The aim of the study was to analyze how cardiovascular risk factors can be modified using nutritionally improved cooked ham enriched with a pool antioxidants influence relevant metabolic targets. Sixty-five untreated subjects (49.2% males, 50.8% females, mean age 40.92 ± 9.03 years) total cholesterol level ≥180 mg/dL or LDL ≥130 participated in 8-weeks randomized, double-blind controlled trial. Participant intervention group (51.5% 48.5% 41.6 9.8 years and BMI 25.1 3.6 kg/m2) consumed (100 g/d) controls (49.9% 53.1% 40.2 8.3 26.3 3.2 received placebo. At 8 weeks, oxidized decreased significantly between experimental placebo groups (p < 0.036). Experimental differences were also significant 0.05). Similar findings malondialdehyde, cholesterol, high-sensitivity C-reactive protein, interleukin 6 observed group. Significant between-group these variables found, except for 6. effects on inflammation oxidation support direct action etiopathogenic atheromatous plaque. We an improvement lipid profiles among subjects.

参考文章(83)
Anna Vogiatzoglou, Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Jeremy P. E. Spencer, Hagen Schroeter, Kay-Tee Khaw, Gunter G. C. Kuhnle, Flavonoid Intake in European Adults (18 to 64 Years) PLOS ONE. ,vol. 10, ,(2015) , 10.1371/JOURNAL.PONE.0128132
A Bertomeu Ruiz, D Zambón Rados, La placa aterogénica: fisiopatología y consecuencias clínicas Medicina Integral. ,vol. 40, pp. 394- 405 ,(2002)
Mehri Jamilian, Fatemeh Foroozanfard, Fereshteh Bahmani, Rezvan Talaee, Mahshid Monavari, Zatollah Asemi, Effects of Zinc Supplementation on Endocrine Outcomes in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial Biological Trace Element Research. ,vol. 170, pp. 271- 278 ,(2016) , 10.1007/S12011-015-0480-7
Piyawan Bunpo, Tracy G. Anthony, Ascorbic acid supplementation does not alter oxidative stress markers in healthy volunteers engaged in a supervised exercise program. Applied Physiology, Nutrition, and Metabolism. ,vol. 41, pp. 175- 180 ,(2016) , 10.1139/APNM-2015-0285
Cristian Del Bo’, Daniela Martini, Marisa Porrini, Dorothy Klimis-Zacas, Patrizia Riso, Berries and oxidative stress markers: an overview of human intervention studies. Food & Function. ,vol. 6, pp. 2890- 2917 ,(2015) , 10.1039/C5FO00657K
Indika Edirisinghe, Britt Burton-Freeman, C. Tissa Kappagoda, Mechanism of the endothelium-dependent relaxation evoked by a grape seed extract. Clinical Science. ,vol. 114, pp. 331- 337 ,(2008) , 10.1042/CS20070264
Luis MBB Estronca, Joao CP Silva, Julio L Sampaio, Andrej Shevchenko, Paul Verkade, Alfin DN Vaz, Winchil LC Vaz, Otilia V Vieira, None, Molecular Etiology of Atherogenesis – In Vitro Induction of Lipidosis in Macrophages with a New LDL Model PLoS ONE. ,vol. 7, pp. e34822- ,(2012) , 10.1371/JOURNAL.PONE.0034822
Ildefonso Rodríguez-Ramiro, María Ángeles Martín, Sonia Ramos, Laura Bravo, Luis Goya, Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells. European Journal of Nutrition. ,vol. 50, pp. 313- 322 ,(2011) , 10.1007/S00394-010-0139-2
Gabriel Virella, Maria F. Lopes-Virella, Atherogenesis and the humoral immune response to modified lipoproteins. Atherosclerosis. ,vol. 200, pp. 239- 246 ,(2008) , 10.1016/J.ATHEROSCLEROSIS.2008.03.025
María Isabel Burgos Alves, Francisco Avilés Plaza, Rebeca Martínez-Tomás, María Sánchez-Campillo, Elvira Larqué, Francisca Pérez-Llamas, Pedro Martínez Hernández, Soledad Parra Pallarés, Oxidized LDL and its correlation with lipid profile and oxidative stress biomarkers in young healthy Spanish subjects Journal of Physiology and Biochemistry. ,vol. 66, pp. 221- 227 ,(2010) , 10.1007/S13105-010-0028-4