Mechanisms of change in brief treatments for borderline personality disorder: a protocol of a randomized controlled trial

摘要: Borderline personality disorder (BPD) is one of the most frequent, debilitating and lethal mental conditions associated with a serious burden disease. Treatment for patients BPD involves structured psychotherapy, may involve brief psychiatric treatment as first-line intervention. No controlled study has assessed effectiveness such Whereas psychotherapy studies in focus on intervention, we still lack an understanding how why these effects are produced from patient process perspective. It therefore utmost importance to treatment-underlying mechanisms change. The present plans apply novel measurement methods assessing change two central psychobiological processes BPD: emotion socio-cognitive processing. uses theory-driven ecologically valid experimental tasks, which take patient’s individual experience anchor, by integrating methodology neurofunctional imagery research. aim this two-arm, randomized test (i.e., symptom reduction) underlying (10 sessions over 4 months), compared usual. Participants (N = 80 BPD) undergo assessments at four points (intake, 2 months, discharge, 12-month follow up). In addition measures, individuals 2-step assessment potential processing): (1) behavioral (2) (for sub-sample) neurofunctional. We hypothesize that explains effects. This easy-to-implement BPD, sophisticated procedure demonstrate critical role processing treatments. will help increase diminish societal disease related early stages treatment. ClinicalTrials.gov: NCT03717818. Registered 24 October 2018). Protocol version {3} number 2 9 February 2018.