Aversive behavior during intraoral intake in male rats.

摘要: Abstract We investigated if the taste of a sucrose solution becomes progressively more aversive during intraoral infusion and this contributes to termination intake in male rats. The display behavior, such as gapes chin rubs, but not headshakes, forelimb flails or orofacial grooming, varied with concentration an intraorally infused quinine hydrochloride (QHCl) increased by time rat rejected 2 M sucrose. Activation rubs brief QHCl advanced rejection given late infusion, blockade gaping anaesthesization oral cavity Xylocain did prolong solution. Headshakes could be elicited stimulating head limbs sucrose, were activated into stomach duodenum glucose jugular hepatic portal vein. Preventing filling gastrointestinal tract (sham feeding) eliminated rubs. It is suggested that increase aversiveness infusion. However, rats can reject absence any behavioral sign aversion none so-called “taste-related” behaviors exclusively dependent upon stimulation receptors cavity.