Evaluating Blood Loss and the Effect of Antiplatelet Treatment in Foot and Ankle Amputations

摘要: The interrelationship between diabetes mellitus and cardiovascular disease is well-documented, and, secondary to the latter, use of antiplatelet therapy. Although associated vascular manifestations are driving forces behind lower extremity amputations, few data available on risks perioperative therapy with foot ankle amputations. goal present study was address surgical effect continuing or discontinuing before and/or amputation. following were retrospectively collected: blood loss, pre- postoperative hematocrit hemoglobin, operative time, amputation type, age, diabetic status, treatment, number transfusions during period. Perioperative defined as exposure aspirin clopidogrel within 3 days surgery. To compare outcomes groups, factors analyzed using bivariate analyses then multivariate regression models: (1) need for transfusions, (2) high loss (>20 mL), (3) volume (4) time. noninferiority continued assessed in terms time a margin 10 minutes mL, respectively. Antiplatelet not statistically significant risk factor any studied analysis. Equivalence testing revealed that inferior Multivariate analysis suggested has no impact transfusion rate,