Hydrothermal synthesis of graphene oxide/multiform hydroxyapatite nanocomposite: its influence on cell cytotoxicity
作者： Claramaría Rodríguez-González , P Salas , L M López-Marín , Blanca Millán-Chiu , Elder De La Rosa
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摘要: In the present study, Graphene oxide/Hydroxyapatite (GO/HAp) nanocomposites were synthesized using a simple hydrothermal method. The synthesis approach involves use of ammonia, thiourea and urea as precipitating agents to obtain three nanocomposites, GO/HApA, GO/HApT GO/HApU, which display HAp nanoparticles with distinct morphologies. structure composition resultant investigated by x-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Raman spectroscopy, Ultraviolet-Visible spectroscopy Transmition Electron Microscopy (TEM). MTT assay was performed test eventual cytotoxicity composites towards NIH-3T3 fibroblast-derived cell line. Important changes in biocompatibility found different ultrastructures, leading description ribbon like nanocrystal-displaying GO new biomaterial interesting features.
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