Side-effects of insect venom immunotherapy: results from an EAACI multicenter study.
作者： H. Mosbech , U. Müller , On Behalf Of The Study Group
DOI: 10.1034/J.1398-9995.2000.00587.X
关键词:
摘要: Background: The effect of venom immunotherapy (VIT) is well documented, but fear systemic side-effects (SE) may prevent its use. study aimed to analyze the character and frequency SE risk factors. Methods: In a prospective study, 19 European centers included patients starting on VIT for reactions insect stings. Various dose regimens were applied. Results: Data from 840 with total 26601 injections obtained. Seventy-one percent treated Vespula-venom extract 27% honeybee-venom extract. Twenty had corresponding 1.9% during increase 0.5% maintenance phase. vast majority 280 mild: only one-third required medical treatment. Injected or inhaled adrenaline was applied in six patients, whom one drop blood pressure collapse. Female sex, bee-venom extract, rapid increase, not severity sting reactions, increased SE. less males related age, treatment phase, species insect, reactions. Conclusions: low, thesecould be managed without Risk females, bee-venom-treated those increase.
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