Interferon Regulatory Factor 9 Protects Against Cardiac Hypertrophy by Targeting Myocardin

作者: Ding-Sheng Jiang , Yu-Xuan Luo , Ran Zhang , Xiao-Dong Zhang , Hou-Zao Chen

DOI: 10.1161/HYPERTENSIONAHA.113.02083

关键词:

摘要: … IRF9 as an endogenous negative regulator of cardiac hypertrophy and observed that IRF9 was … Compared with the controls, the IRF9-deficient mice developed more severe hypertrophy …

参考文章(40)
David Piwnica-Worms, Christina M. Pica, Kathryn E. Luker, Robert D. Schreiber, Overexpression of IRF9 Confers Resistance to Antimicrotubule Agents in Breast Cancer Cells Cancer Research. ,vol. 61, pp. 6540- 6547 ,(2001)
Jun Eguchi, Xun Wang, Songtao Yu, Erin E. Kershaw, Patricia C. Chiu, Joanne Dushay, Jennifer L. Estall, Ulf Klein, Eleftheria Maratos-Flier, Evan D. Rosen, Transcriptional control of adipose lipid handling by IRF4. Cell Metabolism. ,vol. 13, pp. 249- 259 ,(2011) , 10.1016/J.CMET.2011.02.005
Zhouyan Bian, Jun Cai, Di-fei Shen, Li Chen, Ling Yan, Qizhu Tang, Hongliang Li, Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis. Journal of Cellular and Molecular Medicine. ,vol. 13, pp. 1302- 1313 ,(2009) , 10.1111/J.1582-4934.2008.00633.X
Jennifer Zurney, Kristina E. Howard, Barbara Sherry, Basal Expression Levels of IFNAR and Jak-STAT Components Are Determinants of Cell-Type-Specific Differences in Cardiac Antiviral Responses Journal of Virology. ,vol. 81, pp. 13668- 13680 ,(2007) , 10.1128/JVI.01172-07
Hideharu Tomita, Michael Nazmy, Katsuya Kajimoto, Ghassan Yehia, Carlos A. Molina, Junichi Sadoshima, Inducible cAMP Early Repressor (ICER) Is a Negative-Feedback Regulator of Cardiac Hypertrophy and an Important Mediator of Cardiac Myocyte Apoptosis in Response to β-Adrenergic Receptor Stimulation Circulation Research. ,vol. 93, pp. 12- 22 ,(2003) , 10.1161/01.RES.0000079794.57578.F1
David Savitsky, Tomohiko Tamura, Hideyuki Yanai, Tadatsugu Taniguchi, Regulation of immunity and oncogenesis by the IRF transcription factor family Cancer Immunology, Immunotherapy. ,vol. 59, pp. 489- 510 ,(2010) , 10.1007/S00262-009-0804-6
Hiroshi Akazawa, Issei Komuro, Roles of Cardiac Transcription Factors in Cardiac Hypertrophy Circulation Research. ,vol. 92, pp. 1079- 1088 ,(2003) , 10.1161/01.RES.0000072977.86706.23
Jun Zhou, Xing-Hua Liao, Chenyu Wu, Junyan Li, Rui Xiao, Cailian Cheng, Nan Wang, Dongsun Cao, Tong-Cun Zhang, The synergistic effects of cytomegalovirus IE2 and myocardin on cardiomyocyte hypertrophy FEBS Letters. ,vol. 585, pp. 1082- 1088 ,(2011) , 10.1016/J.FEBSLET.2011.03.007
R. McKendry, J. John, D. Flavell, M. Muller, I. M. Kerr, G. R. Stark, High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 11455- 11459 ,(1991) , 10.1073/PNAS.88.24.11455
Richard Treisman, Ternary complex factors: growth factor regulated transcriptional activators. Current Opinion in Genetics & Development. ,vol. 4, pp. 96- 101 ,(1994) , 10.1016/0959-437X(94)90097-3