Transfer hydrogenation; a convenient method for removal of some commonly used protecting groups in peptide synthesis

摘要: N-Benzyloxycarbonyl and benzyl ester groups in peptides can be conveniently removed by transfer hydrogenation with cyclohexene 10% palladium–carbon catalyst. If freshly prepared palladium black catalyst is used, other commonly used protecting like Nτ-benzyl (histidine), ether (tyrosine, serine), nitro (arginine) also much more rapidly than the case of usually employed catalytic hydrogenation.