Anti-infective agents against intracellular pathogens
作者： John S. Gunn , Larry S. Schlesinger , Dasheng Wang , Hao-Chieh Chiu , Ching-Shih Chen
DOI:
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摘要: A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors Formula I: wherein X wherein is —CF 3 , Ar selected from and R where R′ L-Lys, D-Lys, β-Ala, L-Lue, L-Ile, Phe, SO 2 CH NH Asn, Glu or Gyl, and R″ methyl, ethyl, allyl, OH, CN, CONH
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