Surface glycoproteins of normal and transformed cells: a difference determined by sialic acid and a growth-dependent sialyl transferase.

作者: L. Warren , J. P. Fuhrer , C. A. Buck

DOI: 10.1073/PNAS.69.7.1838

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摘要: The pattern of elution from a column Sephadex G-50 fucose-labeled carbohydrate component derived the surface glycoproteins transformed cells can be altered to resemble that untransformed by enzymatic removal sialic acid. These results indicate consistent differences found between control and virus-transformed may depend upon relatively specific sialyl transferase is in greater amounts (2.5- 11-times) than cells, dividing as compared nondividing cells.

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