Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism.

作者: Yu-Show Fu , Yun-Chih Cheng , Maan-Yuh Anya Lin , Henrich Cheng , Pei-Ming Chu

DOI: 10.1634/STEMCELLS.2005-0053

关键词:

摘要: … hours in 4% paraformaldehyde in PBS at 4C and then sectioned. Next, the specimens … C, then in 15% sucrose in PBS for 4 hours at 4C, and finally in 20% sucrose in PBS overnight at 4C…

参考文章(54)
P. Brundin, O.G. Nilsson, F.H. Gage, A. Bj�rklund, Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons Experimental Brain Research. ,vol. 60, pp. 204- 208 ,(1985) , 10.1007/BF00237035
Hwai-Shi Wang, Shih-Chieh Hung, Shu-Tine Peng, Chun-Chieh Huang, Hung-Mu Wei, Yi-Jhih Guo, Yu-Show Fu, Mei-Chun Lai, Chin-Chang Chen, Mesenchymal Stem Cells in the Wharton's Jelly of the Human Umbilical Cord Stem Cells. ,vol. 22, pp. 1330- 1337 ,(2004) , 10.1634/STEMCELLS.2004-0013
Henry T. Greely, Thomas Hamm, Rodney Johnson, Carole R. Price, Randy Weingarten, Thomas Raffin, The Ethical Use of Human Fetal Tissue in Medicine The New England Journal of Medicine. ,vol. 320, pp. 1093- 1096 ,(1989) , 10.1056/NEJM198904203201624
Yu-Show Fu, Yu-Tsung Shih, Yun-Chih Cheng, Ming-Yuan Min, Transformation of Human Umbilical Mesenchymal Cells into Neurons in vitro Journal of Biomedical Science. ,vol. 11, pp. 652- 660 ,(2004) , 10.1007/BF02256131
Tamir Ben-Hur, Maria Idelson, Hanita Khaner, Martin Pera, Etti Reinhartz, Anna Itzik, Benjamin E. Reubinoff, Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats. Stem Cells. ,vol. 22, pp. 1246- 1255 ,(2004) , 10.1634/STEMCELLS.2004-0094
Shigeo Okabe, Karin Forsberg-Nilsson, A. Cyril Spiro, Menahem Segal, Ronald D.G. McKay, DEVELOPMENT OF NEURONAL PRECURSOR CELLS AND FUNCTIONAL POSTMITOTIC NEURONS FROM EMBRYONIC STEM CELLS IN VITRO Mechanisms of Development. ,vol. 59, pp. 89- 102 ,(1996) , 10.1016/0925-4773(96)00572-2
D. J. Clarke, P. Brundin, R. E. Strecker, O. G. Nilsson, A. Bj�rklund, O. Lindvall, Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry. Experimental Brain Research. ,vol. 73, pp. 115- 126 ,(1988) , 10.1007/BF00279666