Impact of Florida's prescription drug monitoring program and pill mill law on high-risk patients: A comparative interrupted time series analysis.

摘要: PURPOSE We quantified the effects of Florida's prescription drug monitoring program and pill mill law on high-risk patients. METHODS used QuintilesIMS LRx Lifelink data to identify patients receiving opioids in Florida (intervention state, N: 1.13 million) Georgia (control 0.54 million). The preintervention, intervention, postintervention periods were July 2010 June 2011, 2011 September October 2012. identified 3 types patients: (1) concomitant users: with use benzodiazepines opioids; (2) chronic long-term, high-dose, opioid users; (3) shoppers: from multiple sources. compared changes prescriptions between before after policy implementation among high-risk/low-risk Our monthly measures included average morphine milligram equivalent per transaction, total volume across all prescriptions, days supplied (4) number dispensed. RESULTS Among opioid-receiving individuals Florida, 6.62% users, 1.96% 0.46% shoppers. Following implementation, experienced relative reductions (opioid -1.08 mg/month, 95% confidence interval [CI] -1.62 -0.54), (chronic -4.58 kg/month, CI -5.41 -3.76), dispensed (concomitant -640 prescriptions/month, -950 -340). Low-risk generally did not experience statistically significantly reductions. CONCLUSIONS Compared Georgia, associated large utilization