Multicomponent Reactions, Union of MCRs and Beyond

作者: Tryfon Zarganes-Tzitzikas , Ajay L. Chandgude , Alexander Dömling

DOI: 10.1002/TCR.201500201

关键词:

摘要: Multicomponent reactions (MCRs), which are located between one- and two-component polymerization reactions, provide a number of valuable conceptual synthetic advantages over stepwise sequential approaches towards complex molecules. To address current limitations in the MCRs resulting scaffolds, concept union was introduced two decades ago by Domling Ugi is rapidly advancing, as apparent several recently published works. MCR technology now widely recognized for its impact on drug discovery projects strongly endorsed industry addition to academia. Clearly, novel scaffolds accessible few steps including will further enhance field applications. Additionally, broad expansion applications fields such imaging, materials science, medical devices, agriculture, or futuristic stem cell therapy theragnostics solar energy superconductivity predicted.

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