The utility of the history and clinical signs of poisoning in childhood: A prospective study

摘要: The authors aimed to evaluate the utility of history and clinical signs for predicting ingestion poisons in children. A prospective cohort study was performed all patients presenting with suspected poisoning a pediatric emergency department over 13-month period. Clinical data were collected on preformatted consultation sheet. Urine drug screens (UDS) analyzed by gas chromatography/mass spectrometry (GC/MS). Serum toxicologic tests when clinically indicated. sensitivity, specificity, positive predictive values (PPV), negative (NPV) calculated, first using UDS and, second, available as gold standards. Of 249 patients, 110 (46%) had performed. purported poison ingested potentially identifiable GC/MS 57 (52%) these UDS. Only results from included our statistical analysis. Overall, identified 33 (58%) Similarly, less than 5 years age subgroup, 28 (56%) 50 positive. Odor breath (PPV 100%), followed symptoms consistent 92%) presence clothes 86%) most useful predictors Similar obtained used standard. best poisonous children found be odor breath, poisoning, patient's clothes. Approximately 40% who present have not been exposed putative toxin.