Heterogeneous Modulation of Place Cell Firing by Changes in Context

摘要: Hippocampal place cells show spatially localized activity that can be modulated by both geometric information (e.g., the distances and directions of features in environment) nongeometric colors, odors, possibly behaviors). Nongeometric may allow discrimination different spatial contexts. Understanding how (or contextual) affects hippocampal is important light proposals hippocampus play a role constructing representation context. We investigated contextual modulation cell recording while rats foraged compound contexts comprising black or white color paired with lemon vanilla odor. Some responded to odor changes alone, but most varying combinations both. Thus, we demonstrate, for first time, there heterogeneous input inputs into hippocampus. propose model remapping which are selectively activated subsets stimuli. Because it appears affected stimuli, entire context would require at population level, supporting