Randomized Control Trial to Improve Adiposity and Insulin Resistance in Overweight Latino Adolescents

摘要: Few randomized trials attempt to improve insulin sensitivity and associated metabolic risks in overweight Latino youth. The purpose of this study is examine the effects a modified carbohydrate nutrition program combined with strength training on sensitivity, adiposity, other type 2 diabetes risk factors adolescents. In 16-week trial, 54 adolescents (15.5 +/- 1.0 years) were randomly assigned to: (i) Control (C; n = 16), (ii) Nutrition (N; 21), or (iii) + Strength (N+ST; 17). N group received classes (once per week), while N+ST same plus (twice week). following measured at pre- postintervention: by 1-repetition maximum, dietary intake 3-day records, body composition dual-energy X-ray absorptiometry, glucose/insulin indices oral glucose tolerance test (OGTT) intravenous minimal modeling. Across intervention tested using analysis covariance post hoc pairwise comparisons. A significant overall effect was found for improvement bench press (P < 0.001) reductions energy 0.05), 0.04) fat 0.03). There no composition, most exception incremental area under curve (IAUC) which decreased 18 6.3% compared 32% increase C group. conclusion, intense, culturally tailored resulted beneficial glycemic response glucose.