Conditioning Regimens for Cord Blood Transplantation
作者： Kelly Ross , Jonathan Gutman
DOI: 10.1007/978-3-319-53628-6_6
关键词:
摘要: Conditioning regimens prior to allogeneic hematopoietic cell transplantation (allo-HCT) serve suppress the patient’s immune system allow infused progenitor and stem cells engraft and, in case of malignant diseases, target residual disease reduce relapse risk. vary intensity; higher-intensity result increased risk acute toxicity potential regimen-related mortality, while lower-intensity graft failure. This chapter reviews myeloablative, reduced-intensity, nonmyeloablative conditioning used cord blood treat nonmalignant neoplastic diseases. Special consideration is given questions related role antithymocyte globulin as well strategies optimize engraftment.
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