Theoretical aspects of chiral separation in capillary electrophoresis: II. The role of organic solvent

作者: Stephen A.C. Wren , Raymond C. Rowe

DOI: 10.1016/0021-9673(92)80181-S

关键词:

摘要: Previous work in chiral capillary electrophoresis has shown that the addition of methanol to buffer can lead either an increase or decrease separation. This behaviour is explained by a mathematical model. The proposed model supported new on separation propranolol enantiomers using systems containing acetonitrile.

参考文章(19)
Stephen A.C. Wren, Raymond C. Rowe, Theoretical aspects of chiral separation in capillary electrophoresis Journal of Chromatography A. ,vol. 603, pp. 235- 241 ,(1992) , 10.1016/0021-9673(92)85366-2
Koji Otsuka, Junko Kawahara, Kaoru Tatekawa, Shigeru Terabe, Chiral separations by micellar electrokinetic chromatography with sodium N-dodecanoyl-l-valinate Journal of Chromatography A. ,vol. 559, pp. 209- 214 ,(1991) , 10.1016/0021-9673(91)80071-N
David Greatbanks, Roderick Pickford, Cyclodextrins as chiral complexing agents in water, and their application to optical purity measurements Magnetic Resonance in Chemistry. ,vol. 25, pp. 208- 215 ,(1987) , 10.1002/MRC.1260250306
Philippe. Gozel, Ernst. Gassmann, Hope. Michelsen, Richard N. Zare, Electrokinetic resolution of amino acid enantiomers with copper(II)-aspartame support electrolyte Analytical Chemistry. ,vol. 59, pp. 44- 49 ,(1987) , 10.1021/AC00128A009
Michael J. Sepaniak, Roderic O. Cole, Brian K. Clark, Use of native and chemically modified cyclodextrins for the capillary electrophoretic separation of enantiomers Journal of Liquid Chromatography & Related Technologies. ,vol. 15, pp. 1023- 1040 ,(1992) , 10.1080/10826079208018848
Roderic O. Cole, Michael J. Sepaniak, W. L. Hinze, Optimization of binaphthyl enantiomer separations by capillary zone electrophoresis using mobile phases containing bile salts and organic solvent Hrc-journal of High Resolution Chromatography. ,vol. 13, pp. 579- 582 ,(1990) , 10.1002/JHRC.1240130814
John M. Cruickshank, The clinical importance of cardioselectivity and lipophilicity in beta blockers American Heart Journal. ,vol. 100, pp. 160- 178 ,(1980) , 10.1016/0002-8703(80)90112-X
Hiroyuki Nishi, Tsukasa Fukuyama, Shigeru Terabe, Chiral separation by cyclodextrin-modified micellar electrokinetic chromatography Journal of Chromatography A. ,vol. 553, pp. 503- 516 ,(1991) , 10.1016/S0021-9673(01)88522-8