Pathogenesis and Management of Non-Insulin-Dependent Diabetes Mellitus

作者: William C. Duckworth

DOI: 10.1007/978-1-4612-3240-7_4

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摘要: The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) remains uncertain. Although over the past few years many abnormalities present in disease have been identified, mechanism or mechanisms by which these develop not established (Table 4.1). two major that are essentially all patients with overt NIDDM insulin resistance and defective secretion.1 Which is primary an area considerable controversy. Since both NIDDM, assumption may be required for clinical expression this disease. In populations there a high occurrence such as Pima Indians South Pacific islanders, can detected prior to development glucose intolerance detectable secretion.2 This suggests groups, might abnormality, susceptible individuals could ultimately result secretion full NIDDM.

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