Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
作者： Karl S. Peggs , Sergio A. Quezada , Cynthia A. Chambers , Alan J. Korman , James P. Allison
DOI: 10.1084/JEM.20082492
关键词:
摘要: … Two major findings have supported a non–cell autonomous inhibitory function of CTLA-4. The first is the dominant protection against lethal lymphoproliferation afforded by WT mixed …
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