作者: Jayasree Pillarisetti , Ashok Kondur , Anas Alani , Madhu Reddy , Madhuri Reddy
DOI: 10.1016/J.JACC.2014.04.014
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摘要: Objectives The purpose of this study was to identify the predictors left ventricular (LV) recovery in patients with peripartum cardiomyopathy (PPCM) and record rates implantable cardioverter-defibrillator (ICD) use. Background PPCM is a rare, life-threatening disease. use ICDs has not been clearly understood patient group. Identification persistent LV dysfunction can help select at risk for sudden cardiac death. Methods A retrospective conducted 2 academic centers between January 1, 1999, December 31, 2012. Clinical demographic variables delivery records diagnosis (International Classification Diseases, 9th Revision code 674.5) were reviewed. Improvement function noted from echocardiography reports. Results total sample comprised 100 patients, whom 55% African Americans, 39% Caucasians, 6% were Hispanic, mean age 30 ± 6 years. Mean ejection fraction (LVEF) 28 9%. Forty-two percent showed improvement LVEF over duration 33 21 months. Postpartum (hazard ratio: 3.0; p = 0.01) Caucasian/Hispanic race 2.2; LVEF. Only 7 58 (12%) who did have their had an ICD implanted. There 11 deaths, trend toward higher mortality those display improved (15% vs. 5%; 0.1). Conclusions More than one-third women improve delayed majority these patients. Caucasians diagnosed postpartum period appear be most likely recover. rate implantation primary prevention death group low.