Subcellular localization of epidermal growth factor in human submandibular gland.
作者： Margherita Cossu , Maria T. Perra , Marco Piludu , Maria S. Lantini
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摘要: Epidermal growth factor in human submandibular gland was localized at the subcellular level by means of an immunogold staining method. Labelling observed serous acini and ducts. In acini, gold particles were found within secretory granules, indicating that is released into saliva through granule exocytosis. ductal system, most intense reactivity revealed principal cells striated these cells, abundant population small cytoplasmic vesicles specifically stained. Immunoreactive both apically basally, suggesting can release their products not only but also interstitium.
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sci-hub.se 参考文章(25)
Edward W. Gresik, The granular convoluted tubule (GCT) cell of rodent submandibular glands Microscopy Research and Technique. ,vol. 27, pp. 1- 24 ,(1994) , 10.1002/JEMT.1070270102
I. Thesleff, L. Viinikka, L. Saxén, E. Lehtonen, J. Perheentupa, The parotid gland is the main source of human salivary epidermal growth factor. Life Sciences. ,vol. 43, pp. 13- 18 ,(1988) , 10.1016/0024-3205(88)90231-7
Alane Gray, Thomas J. Dull, Axel Ullrich, Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor Nature. ,vol. 303, pp. 722- 725 ,(1983) , 10.1038/303722A0
R A Murphy, A Y Watson, J Metz, W G Forssmann, The mouse submandibular gland: an exocrine organ for growth factors. Journal of Histochemistry & Cytochemistry. ,vol. 28, pp. 890- 902 ,(1980) , 10.1177/28.8.6969274
Dean Falk, Hadar AL 162-28 endocast as evidence that brain enlargement preceded cortical reorganization in hominid evolution Nature. ,vol. 313, pp. 45- 47 ,(1985) , 10.1038/313045A0
DELBERT A. FISHER, JAYARAMAN LAKSHMANAN, Metabolism and effects of epidermal growth factor and related growth factors in mammals. Endocrine Reviews. ,vol. 11, pp. 418- 442 ,(1990) , 10.1210/EDRV-11-3-418
G Palade, Intracellular aspects of the process of protein synthesis Science. ,vol. 189, pp. 347- 358 ,(1975) , 10.1126/SCIENCE.1096303
A. Mouihate, J. Lestage, Epidermal growth factor: a potential paracrine and autocrine system within the pituitary. Neuroreport. ,vol. 6, pp. 1401- 1404 ,(1995) , 10.1097/00001756-199507100-00010
J D Penschow, J P Coghlan, Secretion of glandular kallikrein and renin from the basolateral pole of mouse submandibular duct cells: an immunocytochemical study.: Journal of Histochemistry and Cytochemistry. ,vol. 41, pp. 95- 103 ,(1993) , 10.1177/41.1.8417114
B.L. Slomiany, Z. Fekete, J. Liu, V.L.N. Murty, A. Slomiany, Activation of dihydropyridine-sensitive parotid salivary gland calcium channels by epidermal growth factor. Archives of Oral Biology. ,vol. 37, pp. 863- 868 ,(1992) , 10.1016/0003-9969(92)90055-D