Innate immunity in the small intestine

作者: Rebeca Santaolalla , Maria T. Abreu

DOI: 10.1097/MOG.0B013E3283506559

关键词:

摘要: Purpose of reviewIn this article, we provide an update the latest findings related to innate immunity in small intestine. In particular, will focus on immune receptors and antimicrobial strategies that keep luminal bacteria viral pathogens under control avoid mucosal dama

参考文章(69)
Hirokazu Mayuzumi, Kyoko Inagaki-Ohara, Catherine Uyttenhove, Yuko Okamoto, Goro Matsuzaki, Interleukin-17A is required to suppress invasion of Salmonella enterica serovar Typhimurium to enteric mucosa. Immunology. ,vol. 131, pp. 377- 385 ,(2010) , 10.1111/J.1365-2567.2010.03310.X
Maria T. Abreu, Masayuki Fukata, Moshe Arditi, TLR Signaling in the Gut in Health and Disease The Journal of Immunology. ,vol. 174, pp. 4453- 4460 ,(2005) , 10.4049/JIMMUNOL.174.8.4453
Suzanne Talbot, Sabine Tötemeyer, Masahiro Yamamoto, Shizuo Akira, Katherine Hughes, David Gray, Tom Barr, Pietro Mastroeni, Duncan J. Maskell, Clare E. Bryant, Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar typhimurium infection, but not for the initiation of bacterial clearance. Immunology. ,vol. 128, pp. 472- 483 ,(2009) , 10.1111/J.1365-2567.2009.03146.X
Rachel Cooney, John Baker, Oliver Brain, Benedicte Danis, Tica Pichulik, Philip Allan, David JP Ferguson, Barry J Campbell, Derek Jewell, Alison Simmons, None, NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nature Medicine. ,vol. 16, pp. 90- 97 ,(2010) , 10.1038/NM.2069
Daniel C Baumgart, Simon R Carding, Inflammatory bowel disease: cause and immunobiology The Lancet. ,vol. 369, pp. 1627- 1640 ,(2007) , 10.1016/S0140-6736(07)60750-8
Natalia Shulzhenko, Andrey Morgun, William Hsiao, Michele Battle, Michael Yao, Oksana Gavrilova, Marlene Orandle, Lloyd Mayer, Andrew J Macpherson, Kathy D McCoy, Claire Fraser-Liggett, Polly Matzinger, Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut Nature Medicine. ,vol. 17, pp. 1585- 1593 ,(2011) , 10.1038/NM.2505
S. Vaishnava, C. L. Behrendt, A. S. Ismail, L. Eckmann, L. V. Hooper, Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 20858- 20863 ,(2008) , 10.1073/PNAS.0808723105
Luigi Franchi, Tatjana Eigenbrod, Raúl Muñoz-Planillo, Gabriel Nuñez, The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nature Immunology. ,vol. 10, pp. 241- 247 ,(2009) , 10.1038/NI.1703
Jiliu Xu, William R Treem, Christopher Roman, Virginia Anderson, Richard Rubenstein, Steven M Schwarz, Ileal immune dysregulation in necrotizing enterocolitis: role of CD40/CD40L in the pathogenesis of disease. Journal of Pediatric Gastroenterology and Nutrition. ,vol. 52, pp. 140- 146 ,(2011) , 10.1097/MPG.0B013E3182039BAD
Lesley E. Smythies, Ruizhong Shen, Diane Bimczok, Lea Novak, Ronald H. Clements, Devin E. Eckhoff, Phillipe Bouchard, Michael D. George, William K. Hu, Satya Dandekar, Phillip D. Smith, Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation Journal of Biological Chemistry. ,vol. 285, pp. 19593- 19604 ,(2010) , 10.1074/JBC.M109.069955