Magic-angle-spinning solid-state NMR applied to polypeptides and proteins

作者: Colan E. Hughes , Marc Baldus

DOI: 10.1016/S0066-4103(04)55002-0

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摘要: This chapter deals with the topic of polypeptide structure elucidation using technique magic-angle-spinning (MAS) solid-state NMR. We discuss various aspects sample preparation and recent progress in establishing high-resolution conditions for MAS-based structural studies. Approaches obtaining parameters multiply or uniformly labelled polypeptides are reviewed. Recent applications to globular membrane-associated proteins summarized.

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