Steroid hormone actions in tissue culture cells and cell hybrids--their relation to human malignancies.
作者： E. BRAD THOMPSON , MICHAEL R. NORMAN , MARC E. LIPPMAN
DOI: 10.1016/B978-0-12-571133-3.50020-9
关键词:
摘要: Publisher Summary This chapter discusses steroid sensitivity and resistance within the limits of those cells that appear to have natural sensitivity. The explores how control their responses steroids. different by various receptor-containing a given require additional levels control. is true all steroids; however, it particularly striking in case glucocorticoids, for which receptors been found many tissues. tissue-specific effects glucocorticoids range from induction enzymes inhibition DNA synthesis lymphocytolysis. Thus, while receptor theory action has helped visualize first step path steroids exert multiple effects, not solved entirely problem specificity response.
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