Semantic processing impairment in individuals with schizotypal personality disorder features: A preliminary event-related potential study

作者: Kui Wang , Yi Wang , Chao Yan , Yu-na Wang , Eric F.C. Cheung

DOI: 10.1016/J.PNPBP.2012.08.019

关键词:

摘要: article i nfo Objective: This study aimed to examine semantic processing features in individuals with and without schizotypal personality disorder (SPD) features. Methods: An implicit task was used the automatic spreading activation process which is relatively free from influence of attention. explicit controlled requires high involvement Individuals stable SPD (n=17) were those who scored higher than 36 on questionnaire (SPQ) at two time points. unstable (n=15) defined as participants baseline point but lower second point. Their per- formances tasks then compared 17 (scoring below both points). Event-related potentials (ERP) recorded when performing tasks. Results: Behavioral data, early ERP components N400s analyzed each experiment. No between-group difference observed task. In task, dif- ferences involved only N400 component. When group features, partici- pants showed enhanced effects (difference wave), while there no between groups Moreover, larger found be due less negative amplitudes related target words. Conclusion: These findings suggest that impaired context-related stimuli. The inhibition function contextually unrelated materials appeared intact.

参考文章(32)
Margaret A Niznikiewicz, Martina Voglmaier, Martha E Shenton, Larry J Seidman, Chandlee C Dickey, Richard Rhoads, Enkeat Teh, Robert W McCarley, Electrophysiological Correlates of Language Processing in Schizotypal Personality Disorder American Journal of Psychiatry. ,vol. 156, pp. 1052- 1058 ,(1999) , 10.1176/AJP.156.7.1052
Heribert V. Semlitsch, Peter Anderer, Peter Schuster, Otto Presslich, A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERP. Psychophysiology. ,vol. 23, pp. 695- 703 ,(1986) , 10.1111/J.1469-8986.1986.TB00696.X
Ji-gang Zong, Raymond C.K. Chan, William S. Stone, Xiaolu Hsi, Xiao-yan Cao, Qing Zhao, Yan-fang Shi, Yu-na Wang, Ya Wang, Coping flexibility in young adults: Comparison between subjects with and without schizotypal personality features Schizophrenia Research. ,vol. 122, pp. 185- 192 ,(2010) , 10.1016/J.SCHRES.2010.04.013
Daniel N Allen, Stephen G Huegel, John A Gurklis, Mary E Kelley, Ethan J Barry, Daniel P van Kammen, Utility of WAIS-R short forms in schizophrenia Schizophrenia Research. ,vol. 26, pp. 163- 172 ,(1997) , 10.1016/S0920-9964(97)00052-2
Adrian Raine, Schizotypal personality: neurodevelopmental and psychosocial trajectories. Annual Review of Clinical Psychology. ,vol. 2, pp. 291- 326 ,(2006) , 10.1146/ANNUREV.CLINPSY.2.022305.095318
Crystal R. Blyler, James M. Gold, Virginia N. Iannone, Robert W. Buchanan, Short form of the WAIS-III for use with patients with schizophrenia ☆ Schizophrenia Research. ,vol. 46, pp. 209- 215 ,(2000) , 10.1016/S0920-9964(00)00017-7
Raymond C. K. Chan, Ya Wang, Yongyu Deng, Yani Zhang, Xiaoli Yiao, Cheng Zhang, The Development of a Chinese Equivalence Version of Letter–Number Span Test Clinical Neuropsychologist. ,vol. 22, pp. 112- 121 ,(2008) , 10.1080/13825580601025957