A putative Leishmania panamensis/Leishmania braziliensis hybrid is a causative agent of human cutaneous leishmaniasis in Nicaragua.
作者： A. A. Belli , M. A. Miles , J. M. Kelly
DOI: 10.1017/S0031182000080689
关键词:
摘要: As part of a survey human leishmaniasis in Nicaragua we examined phenotypic and genotypic characteristics 40 Leishmania isolates. We identified 3 distinct parasites associated with cutaneous disease this area; panamensis (40% cases), braziliensis (33%), strain which exhibits the heterozygous isoenzyme DNA fingerprinting patterns expected L. panamensis/L. hybrid (27%). There was complete correlation between data for each putative hybrids examined. All 'hybrids' were obtained from foci northern region country where occur sympatrically. These observations provide strong evidence sexual reproduction New World populations suggest that it is taxonomic epidemiological significance.
sci-hub.se 参考文章(22)
Vanete Thomaz Soccol, Les Leishmania du Nouveau monde : analyse enzymatique, démarche progressive phénétique-cladistique, relations phylogénétiques avec les Leishmania de l'Ancien monde Montpellier 1. ,(1993)
Juan MacFARLANE, Mark L. BLAXTER, Richard P. BISHOP, Michael A. MILES, John M. KELLY, Identification and characterisation of a Leishmania donovani antigen belonging to the 70-kDa heat-shock protein family. FEBS Journal. ,vol. 190, pp. 377- 384 ,(1990) , 10.1111/J.1432-1033.1990.TB15586.X
W. Peters, S. Elbihari, Ching Liu, S.M. Le Blancq, D.A. Evans, R. Killick-Kendrick, V. Smith, C.I. Baldwin, Leishmania infecting man and wild animals in Saudi Arabia. 1. General survey. Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 79, pp. 831- 839 ,(1985) , 10.1016/0035-9203(85)90130-0
A. K. Cruz, R. Titus, S. M. Beverley, Plasticity in chromosome number and testing of essential genes in Leishmania by targeting. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 1599- 1603 ,(1993) , 10.1073/PNAS.90.4.1599
John M. Kelly, Janette M. Law, Caroline J. Chapman, Van Eys Guillaume J.J.M, David A. Evans, Evidence of genetic recombination in Leishmania. Molecular and Biochemical Parasitology. ,vol. 46, pp. 253- 263 ,(1991) , 10.1016/0166-6851(91)90049-C
Stephen J. Jeremiah, Susan Povey, Michael A. Miles, Molecular size of enzymes in Trypanosoma cruzi considered in relationship to the genetic interpretation of isozyme patterns Molecular and Biochemical Parasitology. ,vol. 6, pp. 297- 302 ,(1982) , 10.1016/0166-6851(82)90062-7
Michel Pagès, Patrick Bastien, Francisco Veas, Valérie Rossi, Michel Bellis, Patrick Wincker, Jean-Antoine Rioux, Gérard Roizès, Chromosome size and number polymorphisms in Leishmania infantum suggest amplification/deletion and possible genetic exchange Molecular and Biochemical Parasitology. ,vol. 36, pp. 161- 168 ,(1989) , 10.1016/0166-6851(89)90188-6
LINDSEY J. PANTON, ROBERT B. TESH, KARI C. NADEAU, STEPHEN M. BEVERLEY, A Test for Genetic Exchange in Mixed Infections of Leishmania major in the Sand Fly Phlebotomus papatasi Journal of Eukaryotic Microbiology. ,vol. 38, pp. 224- 228 ,(1991) , 10.1111/J.1550-7408.1991.TB04433.X
Michel Tibayrenc, Leishmania: sex, karyotypes and population genetics. Parasitology Today. ,vol. 8, pp. 305- 306 ,(1992) , 10.1016/0169-4758(92)90102-8
Martin C. Taylor, John M. Kelly, Caroline J. Chapman, Alan H. Fairlamb, Michael A. Miles, The structure, organization, and expression of the Leishmania donovani gene encoding trypanothione reductase. Molecular and Biochemical Parasitology. ,vol. 64, pp. 293- 301 ,(1994) , 10.1016/0166-6851(94)00034-4