The sugar code : fundamentals of glycosciences

摘要: CHEMICAL BASIS The Biochemical Basis and Coding Capacity of the Sugar Code (Rudiger, Gabius) Three-dimensional Aspects (Kozar, Andre, Ulicny, Chemist's Way to Synthesize Glycosides (Oscarson) Prepare Multivalency (Chabre, Roy) Analytical Aspects: Analysis Protein-Bound Glycans (Nakagawa) NATURAL GLYCOSYLATION - GLYCOPROTEINS N-Glycosylation (Zuber, Roth) O-Glycosylation: Structural Diversity Functions (Patsos, Corfield) Glycosylation Model "Lower" Organisms (Wilson, Paschinger, Rendic) Glycosylphosphatidylinositol Anchors: Structure, Biosynthesis (Shams-Eldin, Debierre-Grockiego, Schwarz) GLYCOLIPIDS, PROTEOGLYCANS, CHITIN Glycolipids (Kopitz) Proteoglycans (Buddecke) Chitin (Merzendorfer) PROTEIN-CARBOHYDRATE INTERACTIONS Protein-Carbohydrate Interactions: Basic Concepts Methods for (Solis, Romero, Menendez, Jimenez-Barbero) How Determine Specificity: From Lectin Profiling Glycan Mapping Arrays (Tateno, Kuno, Hirabayashi) History Lectinology Ca2+: Mastermind Active Player Activity (Including a Gallery Folds) (Gabius) Bacterial Viral Lectins (Holgersson, Gustafsson, Gaunitz) Plant Animal Human Routes in Evolution: Case Study on C-Type Lectin-Like Domains (Gready, Zelensky) Carbohydrate-Carbohydrate Interactions (Bucior, Burger, Fernandez-Busquets) BIOMEDICAL ASPECTS AND CASE STUDIES Diseases (Hennet) Models Delineate Functionality (Honke, Taniguchi) Glycobiology Fertilization Early Embryonic Development (Habermann, Sinowatz) as Functional Markers Malignancy? (Andre, Kopitz, Kaltner, Villalobo, Small is Beautiful: Mini-Lectins Host Defense (Lehrer) Inflammation Glycosciences (Schwartz-Albiez) Sugars Pharmaceuticals (Osborn, Turkson) Platelet Glycoproteins Hematology (Hoffmeister, Falet) Neurobiology meets (Ledeen, Wu) COMPANION WEB-SITE: www.wiley-vch.de/home/thesugarcode