Prognostic value of preoperative multiparametric magnetic resonance imaging (MRI) for predicting biochemical recurrence after radical prostatectomy.

作者: Seiya Hattori , Takeo Kosaka , Ryuichi Mizuno , Kent Kanao , Akira Miyajima

DOI: 10.1111/BJU.12329

关键词:

摘要: Objective To evaluate the suitability of preoperative multiparametric magnetic resonance imaging (MRI) positivity as a predictor biochemical recurrence after radical prostatectomy (RP). Patients and Methods We reviewed clinical records patients who underwent either standard RP or laparoscopic between January 2005 December 2009 at our institution. Patients received radiotherapy androgen deprivation therapy before surgery were excluded. A total 314 met study inclusion criteria. Cox proportional hazard regression models used for analyses. In accordance with criteria in established guidelines, radiologist scored probability presence prostate cancer using five-point scale diagnostic confidence level. The highest level any pulse sequence was considered evaluation result. Results MRI significantly associated high stage (cT ≥ 2; P = 0.039), positive biopsy core rate (≥0.2; < 0.001), Gleason score ([GS] ≥8; 0.001) pathological GS (≥8; 0.005). Univariate analysis multivariate showed that MRI prognostic indicator included only variables also including variables. Conclusion Multiparametric can independently predict RP.

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