Calcium signalling: Past, present and future
作者： Ole H Petersen , Marek Michalak , Alexei Verkhratsky , None
DOI: 10.1016/J.CECA.2005.06.023
关键词:
摘要: Ca2+ is a universal second messenger controlling wide variety of cellular reactions and adaptive responses. The initial appreciation as signalling molecule was based on the work Sydney Ringer Lewis Heilbrunn. More recent developments in this field were critically influenced by invention patch clamp technique generation fluorescent indicators. Currently molecular mechanisms are being worked out we beginning to assemble reasonably complete picture overall homeostasis. Furthermore, investigations organellar homeostasis have added complexity our understanding signalling. future lies with detailed integrative function vivo clarification pathology associated malfunctions cascades.
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