AB0 blood group and prognosis in patients with pancreatic cancer

摘要: Although blood group 0 is associated with a reduced risk of pancreatic cancer, little known about the role AB0 antigens in disease progression. We assessed prognostic relevance status large cohort patients resected cancer. A total 627 patients, who underwent resection for ductal adenocarcinoma between October 2001 and December 2008 were enrolled. The relationship outcome was analyzed using univariate multivariate Cox regression analyses. In cancer incidence (31%) lower compared to 13.044 without (38%) (p = 0.0005). There no significant differences clinicopathologic characteristics among different groups. 3-year 5-year overall survival rates 29% 14%. On analysis did not correlate (p = 0.39). Multivariate analysis, however, revealed favorable independent impact on (Hazard ratio 0.78; 95% confidence interval 0.62 – 0.99; p = 0.037). independently prognosis