The Relationship Between Components of Metabolic Syndrome and Open-Angle Glaucoma

摘要: Purpose To determine whether an association exists between various components of metabolic syndrome (diabetes mellitus [DM], systemic arterial hypertension [HTN], hyperlipidemia, and obesity) open-angle glaucoma (OAG) in a large, diverse group individuals throughout the United States. Design Longitudinal cohort study. Participants All beneficiaries aged ≥40 years continuously enrolled managed care network who had 1 or more visits to eye provider during 2001 2007 were identified. Methods Billing codes used identify with OAG those syndrome. Cox regression was hazard developing enrollees individual combinations syndrome, adjustment for sociodemographic factors, medical conditions, other ocular diseases. Main Outcome Measures Hazard OAG. Results Of 2 182 315 met inclusion criteria, 55090 (2.5%) After confounding DM (hazard ratio [HR] = 1.35 [95% confidence interval [CI], 1.21–1.50]) HTN (HR 1.17 CI, 1.13–1.22]) alone combination 1.48 1.39–1.58]) increased relative persons neither these conditions. By contrast, hyperlipidemia 5% decreased 0.95 0.91–0.98]). Comorbid attenuated 1.09 1.05–1.12]) 1.13 1.05–1.21]) Conclusions At time when prevalence disorders States, is increasing this study furthers our understanding risk factors associated helps may be at condition. Financial Disclosure(s) The author(s) have no proprietary commercial interest any materials discussed article.