PHARMACOVIGILANCE STUDY IN GERIATRIC POPULATION

摘要: Objective: Pharmacovigilance is defined as the science and activities concerned with detection, assessment, understanding prevention of adverse reactions to medicines. Main goal pharmacovigilance in geriatric improve safe rational use medicines thereby improving patient care, health society. particularly drug (ADR’s). Hence, a closer studies are much needed older age group due polypharmacy, which can cause ADR’s leading hospital readmission direct indirect treatment cost treat ADR’s. The objective this study was assess prescribing practice patients two or more comorbid condition during stay follow-up on 15th, 30th, 45th, 60th, 75th 90th day after discharge. Methods: conducted Medicine Department, Kempegowda Institute Medical Science Hospital Research Centre, Bengaluru. It non-randomized observational prospective for period 6 months, pattern incidence ADR population. We made an attempt ADRs discharge from by doing follow-ups. Results: Among 50 included study, 29 (58%) were between 60 65 years, out 20 female, 9 found be male patients. Out patients, 40 (37.7%) suffered hypertension, 30 (28.3%) had diabetes mellitus. most commonly used antihypertensive that (33.8%) calcium channel blockers majorly, anti-diabetic drugs, insulin 19 (44.1%) followed 10 (23.2%) who prescribed oral hypoglycemic like metformin. Number drugs per prescription 68% 6-10 drugs. population, we three mild follow-up. During analyzing prescription, totally 122 interactions, 83 (68%) moderate, (25%) (7%) severe interactions. Conclusion: observed monitoring population mandatory their polypharmacy. Follow-up will one step ahead quality life. This reduce readmission, turn economic burden Keywords: Pharmacovigilance, Adverse reactions, Geriatric, Polypharmacy.