Characterization of a new illicit phosphodiesterase-type-5 inhibitor identified in the softgel shell of a dietary supplement.
作者： Takahiro Doi , Kazunaga Takahashi , Midori Yamazaki , Akiko Asada , Akihiro Takeda
DOI: 10.1016/J.JPBA.2018.08.031
关键词:
摘要: Abstract A new sildenafil analog has been identified in the softgel shell of a dietary supplement. The compound was investigated by UV spectroscopy and high-resolution MS analysis, leading to proposed structure 1-methyl-5-{5-[2-(4-methylpiperazin-1-yl)acetyl]-2-propoxyphenyl}-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one. synthetic reference with prepared, two sets analytical data were compared, confirming compound. named propoxyphenyl noracetildenafil from its similarity known
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