The Decipher Genomic Classifier Independently Improves Prognostication for Patients After Prostatectomy

R. Jeffrey Karnes, Eric J. Bergstralh, Elai Davicioni, Mercedeh Ghadessi, Christine Buerki, Anirban P. Mitra, Anamaria Crisan, Nicholas Erho, Ismael A. Vergara, Lucia L. Lam, Rachel Carlson, Darby J.S. Thompson, Zaid Haddad, Benedikt Zimmermann, Thomas Sierocinski, Timothy J. Triche, Thomas Kollmeyer, Karla V. Ballman, Peter C. Black, George G. Klee, Robert B. Jenkins, Validation of a Genomic Classifier that Predicts Metastasis Following Radical Prostatectomy in an At Risk Patient Population Journal of Urology. ,vol. 190, pp. 2047- 2053 ,(2013) , 10.1016/J.JURO.2013.06.017

Nicholas Erho, Anamaria Crisan, Ismael A. Vergara, Anirban P. Mitra, Mercedeh Ghadessi, Christine Buerki, Eric J. Bergstralh, Thomas Kollmeyer, Stephanie Fink, Zaid Haddad, Benedikt Zimmermann, Thomas Sierocinski, Karla V. Ballman, Timothy J. Triche, Peter C. Black, R. Jeffrey Karnes, George Klee, Elai Davicioni, Robert B. Jenkins, Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy PLoS ONE. ,vol. 8, pp. e66855- ,(2013) , 10.1371/JOURNAL.PONE.0066855

Derya Tilki, Philipp Mandel, Thorsten Schlomm, Felix K.-H. Chun, Pierre Tennstedt, Dirk Pehrke, Alexander Haese, Hartwig Huland, Markus Graefen, Georg Salomon, External validation of the CAPRA-S score to predict biochemical recurrence, metastasis and mortality after radical prostatectomy in a European cohort. The Journal of Urology. ,vol. 193, pp. 1970- 1975 ,(2015) , 10.1016/J.JURO.2014.12.020

Scott E Eggener, Peter T Scardino, Patrick C Walsh, Misop Han, Alan W Partin, Bruce J Trock, Zhaoyong Feng, David P Wood, James A Eastham, Ofer Yossepowitch, Danny M Rabah, Michael W Kattan, Changhong Yu, Eric A Klein, Andrew J Stephenson, None, Predicting 15-Year Prostate Cancer Specific Mortality After Radical Prostatectomy Journal of Urology. ,vol. 185, pp. 869- 875 ,(2011) , 10.1016/J.JURO.2010.10.057

Matthew R. Cooperberg, Elai Davicioni, Anamaria Crisan, Robert B. Jenkins, Mercedeh Ghadessi, R. Jeffrey Karnes, Combined Value of Validated Clinical and Genomic Risk Stratification Tools for Predicting Prostate Cancer Mortality in a High-risk Prostatectomy Cohort European Urology. ,vol. 67, pp. 326- 333 ,(2015) , 10.1016/J.EURURO.2014.05.039

Stephen J. Freedland, Voleak Choeurng, Lauren Howard, Amanda De Hoedt, Marguerite du Plessis, Kasra Yousefi, Lucia L. Lam, Christine Buerki, Seong Ra, Bruce Robbins, Edouard J. Trabulsi, Nikhil L. Shah, Firas Abdollah, Felix Y. Feng, Elai Davicioni, Adam P. Dicker, Robert J. Karnes, Robert B. Den, Utilization of a Genomic Classifier for Prediction of Metastasis Following Salvage Radiation Therapy after Radical Prostatectomy European Urology. ,vol. 70, pp. 588- 596 ,(2016) , 10.1016/J.EURURO.2016.01.008

R. Jeffrey Karnes, Voleak Choeurng, Ashley E. Ross, Edward M. Schaeffer, Eric A. Klein, Stephen J. Freedland, Nicholas Erho, Kasra Yousefi, Mandeep Takhar, Elai Davicioni, Matthew R. Cooperberg, Bruce J. Trock, Validation of a Genomic Risk Classifier to Predict Prostate Cancer-specific Mortality in Men with Adverse Pathologic Features. European Urology. ,vol. 73, pp. 168- 175 ,(2018) , 10.1016/J.EURURO.2017.03.036

Daniel E. Spratt, Kasra Yousefi, Samineh Deheshi, Ashley E. Ross, Robert B. Den, Edward M. Schaeffer, Bruce J. Trock, Jingbin Zhang, Andrew G. Glass, Adam P. Dicker, Firas Abdollah, Shuang G. Zhao, Lucia L.C. Lam, Marguerite du Plessis, Voleak Choeurng, Zaid Haddad, Christine Buerki, Elai Davicioni, Sheila Weinmann, Stephen J. Freedland, Eric A. Klein, R. Jeffrey Karnes, Felix Y. Feng, Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease Journal of Clinical Oncology. ,vol. 35, pp. 1991- 1998 ,(2017) , 10.1200/JCO.2016.70.2811

Deepansh Dalela, María Santiago-Jiménez, Kasra Yousefi, R. Jeffrey Karnes, Ashley E. Ross, Robert B. Den, Stephen J. Freedland, Edward M. Schaeffer, Adam P. Dicker, Mani Menon, Alberto Briganti, Elai Davicioni, Firas Abdollah, Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model Journal of Clinical Oncology. ,vol. 35, pp. 1982- 1990 ,(2017) , 10.1200/JCO.2016.69.9918