The evolution and adaptation of A-to-I RNA editing
作者： Arielle L. Yablonovitch , Patricia Deng , Dionna Jacobson , Jin Billy Li
DOI: 10.1371/JOURNAL.PGEN.1007064
关键词:
摘要: Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to protein. can generate a multitude of transcript isoforms and potentially be used optimize protein function in response varying conditions. In light this fact millions sites have been identified many different species, it interesting examine extent which these evolved functionally important. review, we discuss results pertaining evolution editing, specifically humans, cephalopods, Drosophila. We focus on how comparative genomics approaches aided identification are likely advantageous. The use as mechanism adapt environmental conditions will also reviewed.
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sci-hub.st 参考文章(67)
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