Lead compounds from nature: Synthesis of natural xanthones and chroman aldehydes that inhibit HIV-1

Raphaël Robiette, Jeffery Richardson, Varinder K. Aggarwal, Jeremy N. Harvey, On the Origin of High E Selectivity in the Wittig Reaction of Stabilized Ylides: Importance of Dipole-Dipole Interactions Journal of the American Chemical Society. ,vol. 127, pp. 13468- 13469 ,(2005) , 10.1021/JA0539589

J. R. Lewis, B. H. Warrington, 974. Oxidative coupling. Part VI. Synthesis of xanthones Journal of the Chemical Society (Resumed). pp. 5074- 5077 ,(1964) , 10.1039/JR9640005074

B. E. Evans, K. E. Rittle, M. G. Bock, R. M. DiPardo, R. M. Freidinger, W. L. Whitter, G. F. Lundell, D. F. Veber, P. S. Anderson, R. S. L. Chang, V. J. Lotti, D. J. Cerino, T. B. Chen, P. J. Kling, K. A. Kunkel, J. P. Springer, J. Hirshfield, Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists Journal of Medicinal Chemistry. ,vol. 31, pp. 2235- 2246 ,(1988) , 10.1021/JM00120A002

Hung The Nguyen, Marie-Christine Lallemand, Sabrina Boutefnouchet, Sylvie Michel, François Tillequin, Antitumor Psoropermum xanthones and Sarcomelicope acridones: privileged structures implied in DNA alkylation. Journal of Natural Products. ,vol. 72, pp. 527- 539 ,(2009) , 10.1021/NP800644Y

Vinod K. Ahluwalia, Krishnan K. Arora, Ravinder S. Jolly, Acid-catalysed condensation of isoprene with phenols. Formation of 2,2-dimethylchromans Journal of the Chemical Society, Perkin Transactions 1. ,vol. 13, pp. 335- 338 ,(1982) , 10.1039/P19820000335

L.C. Santos, S. Piacente, F. De Riccardis, A.M. Eletto, C. Pizza, W. Vilegas, Xanthones and flavonoids from Leiothrix curvifolia and Leiothrix flavescens. Phytochemistry. ,vol. 56, pp. 853- 856 ,(2001) , 10.1016/S0031-9422(00)00480-5

Thomas B.P. Oldenburg, Heinz Wilkes, Brian Horsfield, Adri C.T. van Duin, Daniel Stoddart, Arnd Wilhelms, Xanthones—novel aromatic oxygen-containing compounds in crude oils Organic Geochemistry. ,vol. 33, pp. 595- 609 ,(2002) , 10.1016/S0146-6380(02)00015-3

W GREENE, Z DEBYSER, Y IKEDA, E FREED, E STEPHENS, W YONEMOTO, R BUCKHEIT, J ESTE, T CIHLAR, Novel targets for HIV therapy. Antiviral Research. ,vol. 80, pp. 251- 265 ,(2008) , 10.1016/J.ANTIVIRAL.2008.08.003

David A. Shirley, James R. Johnson, John P. Hendrix, Product distribution in the metalation of some aromatic substrates with n-butyllithium Journal of Organometallic Chemistry. ,vol. 11, pp. 209- 216 ,(1968) , 10.1016/0022-328X(68)80043-9

P. K. Grover, G. D. Shah, R. C. Shah, Xanthones. Part IV. A new synthesis of hydroxyxanthones and hydroxybenzophenones Journal of The Chemical Society (resumed). pp. 3982- 3985 ,(1955) , 10.1039/JR9550003982