Trametinib Toxicities in Patients With Low-grade Gliomas and Diabetes Insipidus: Related Findings?
作者： Grace Egan , Jill Hamilton , Tara McKeown , Eric Bouffet , Uri Tabori
DOI: 10.1097/MPH.0000000000001427
关键词:
摘要: … trametinib was 138 mmol/L (reference range: 135 to 143 mmol/L). Within 1 week of starting trametinib … of 4, indicating possible causality between the adverse reactions and trametinib. …
lww.com
sci-hub.se 参考文章(19)
K E Duncan, L Y Chang, M Patronas, MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicity Eye. ,vol. 29, pp. 1003- 1012 ,(2015) , 10.1038/EYE.2015.82
Hans J. Schaeffer, Michael J. Weber, Mitogen-activated protein kinases: specific messages from ubiquitous messengers Molecular and Cellular Biology. ,vol. 19, pp. 2435- 2444 ,(1999) , 10.1128/MCB.19.4.2435
Kenar D. Jhaveri, Vipulbhai Sakhiya, Steven Fishbane, Nephrotoxicity of the BRAF Inhibitors Vemurafenib and Dabrafenib JAMA Oncology. ,vol. 1, pp. 1133- 1134 ,(2015) , 10.1001/JAMAONCOL.2015.1713
Fuminori Umenishi, Robert W. Schrier, Hypertonicity-induced Aquaporin-1 (AQP1) Expression Is Mediated by the Activation of MAPK Pathways and Hypertonicity-responsive Element in the AQP1 Gene Journal of Biological Chemistry. ,vol. 278, pp. 15765- 15770 ,(2003) , 10.1074/JBC.M209980200
K Oshio, D.K Binder, B Yang, S Schecter, A.S Verkman, G.T Manley, Expression of aquaporin water channels in mouse spinal cord. Neuroscience. ,vol. 127, pp. 685- 693 ,(2004) , 10.1016/J.NEUROSCIENCE.2004.03.016
S. Nielsen, C. L. Chou, D. Marples, E. I. Christensen, B. K. Kishore, M. A. Knepper, Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 1013- 1017 ,(1995) , 10.1073/PNAS.92.4.1013
Qin Jiang, Cong Cao, Shan Lu, Rebecca Kivlin, Brittany Wallin, Wenming Chu, Zhigang Bi, Xinru Wang, Yinsheng Wan, MEK/ERK pathway mediates UVB-induced AQP1 downregulation and water permeability impairment in human retinal pigment epithelial cells International Journal of Molecular Medicine. ,vol. 23, pp. 771- 777 ,(2009) , 10.3892/IJMM_00000191
Marios C. Papadopoulos, A. S. Verkman, Aquaporin-4 Gene Disruption in Mice Reduces Brain Swelling and Mortality in Pneumococcal Meningitis * Journal of Biological Chemistry. ,vol. 280, pp. 13906- 13912 ,(2005) , 10.1074/JBC.M413627200
S Nielsen, B L Smith, E I Christensen, M A Knepper, P Agre, CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. Journal of Cell Biology. ,vol. 120, pp. 371- 383 ,(1993) , 10.1083/JCB.120.2.371
Jinghui Zhang, Gang Wu, Claudia P Miller, Ruth G Tatevossian, James D Dalton, Bo Tang, Wilda Orisme, Chandanamali Punchihewa, Matthew Parker, Ibrahim Qaddoumi, Fredrick A Boop, Charles Lu, Cyriac Kandoth, Li Ding, Ryan Lee, Robert Huether, Xiang Chen, Erin Hedlund, Panduka Nagahawatte, Michael Rusch, Kristy Boggs, Jinjun Cheng, Jared Becksfort, Jing Ma, Guangchun Song, Yongjin Li, Lei Wei, Jianmin Wang, Sheila Shurtleff, John Easton, David Zhao, Robert S Fulton, Lucinda L Fulton, David J Dooling, Bhavin Vadodaria, Heather L Mulder, Chunlao Tang, Kerri Ochoa, Charles G Mullighan, Amar Gajjar, Richard Kriwacki, Denise Sheer, Richard J Gilbertson, Elaine R Mardis, Richard K Wilson, James R Downing, Suzanne J Baker, David W Ellison, St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project, Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas Nature Genetics. ,vol. 45, pp. 602- 612 ,(2013) , 10.1038/NG.2611