摘要: The most advanced candidate vaccine against dengue viruses, called CYD-TDV, is progressing toward potential registration and review by the World Health Organization (WHO) in 2016. CYD-TDV a formulation of four chimeric yellow fever 17D each one engineered to express surface envelope prM (membrane) proteins from serotypes virus. protein target virus-neutralizing antibodies. safety efficacy after administration three doses over 12-month period was recently measured two pediatric phase 3 trials Latin America1 Southeast Asia.2 . . .
sci-hub.se 参考文章(5)
Sri Rezeki Hadinegoro, Jose Luis Arredondo-García, Maria Rosario Capeding, Carmen Deseda, Tawee Chotpitayasunondh, Reynaldo Dietze, HI Hj Muhammad Ismail, Humberto Reynales, Kriengsak Limkittikul, Doris Maribel Rivera-Medina, Huu Ngoc Tran, Alain Bouckenooghe, Danaya Chansinghakul, Margarita Cortés, Karen Fanouillere, Remi Forrat, Carina Frago, Sophia Gailhardou, Nicholas Jackson, Fernando Noriega, Eric Plennevaux, T Anh Wartel, Betzana Zambrano, Melanie Saville, None, Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease The New England Journal of Medicine. ,vol. 373, pp. 1195- 1206 ,(2015) , 10.1056/NEJMOA1506223
Adwoa D Bentsi-Enchill, Julia Schmitz, Robert Edelman, Anna Durbin, John T Roehrig, Peter G Smith, Joachim Hombach, Jeremy Farrar, Live Dengue Vaccines Technical Consultation Reporting Group, None, Long-term safety assessment of live attenuated tetravalent dengue vaccines: deliberations from a WHO technical consultation. Vaccine. ,vol. 31, pp. 2603- 2609 ,(2013) , 10.1016/J.VACCINE.2013.03.038
A. P. Durbin, S. S. Whitehead, The Dengue Human Challenge Model: Has the Time Come to Accept This Challenge? The Journal of Infectious Diseases. ,vol. 207, pp. 697- 699 ,(2013) , 10.1093/INFDIS/JIS749
Maria Rosario Capeding, Ngoc Huu Tran, Sri Rezeki S Hadinegoro, Hussain Imam HJ Muhammad Ismail, Tawee Chotpitayasunondh, Mary Noreen Chua, Chan Quang Luong, Kusnandi Rusmil, Dewa Nyoman Wirawan, Revathy Nallusamy, Punnee Pitisuttithum, In-Kyu Yoon, Diane Van Der Vliet, Edith Langevin, Thelma Laot, Yanee Hutagalung, Carina Frago, Mark Boaz, T Anh Wartel, Nadia G Tornieporth, Melanie Saville, Alain Bouckenooghe, None, Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial The Lancet. ,vol. 384, pp. 1358- 1365 ,(2014) , 10.1016/S0140-6736(14)61060-6
Luis Villar, Gustavo Horacio Dayan, José Luis Arredondo-García, Doris Maribel Rivera, Rivaldo Cunha, Carmen Deseda, Humberto Reynales, Maria Selma Costa, Javier Osvaldo Morales-Ramírez, Gabriel Carrasquilla, Luis Carlos Rey, Reynaldo Dietze, Kleber Luz, Enrique Rivas, Maria Consuelo Miranda Montoya, Margarita Cortés Supelano, Betzana Zambrano, Edith Langevin, Mark Boaz, Nadia Tornieporth, Melanie Saville, Fernando Noriega, None, Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America The New England Journal of Medicine. ,vol. 372, pp. 113- 123 ,(2015) , 10.1056/NEJMOA1411037