Determining the oncological risk of autologous lipoaspirate grafting for post-mastectomy breast reconstruction.

作者: Gino Rigotti , Alessandra Marchi , Paolo Stringhini , Guido Baroni , Mirco Galiè

DOI: 10.1007/S00266-010-9481-2

关键词:

摘要: This study compares the incidence of local and regional recurrence breast cancer between two contiguous time windows in a homogeneous population 137 patients who underwent fat tissue transplant after modified radical mastectomy. Median follow-up was 7.6 years period divided into windows, first starting at date mastectomy ending lipoaspirate grafting session second beginning end total time. Although this did not employ an independent control group, found to be comparable periods line with data from similar patient populations enrolled large multicenter clinical trials undergo postsurgical grafting. Statistical comparison disease-free survival curves revealed no significant differences relapse rate subgroups before further confirmation is needed randomized trials, our results support hypothesis that autologous combines striking regenerative properties or marginal effects on probability post-mastectomy locoregional cancer.

参考文章(10)
Sydney R. Coleman, Structural fat grafting: more than a permanent filler. Plastic and Reconstructive Surgery. ,vol. 118, ,(2006) , 10.1097/01.PRS.0000234610.81672.E7
Frank Trepsat, Periorbital rejuvenation combining fat grafting and blepharoplasties. Aesthetic Plastic Surgery. ,vol. 27, pp. 243- 253 ,(2003) , 10.1007/S00266-003-2126-Y
Sydney R Coleman, Hand rejuvenation with structural fat grafting. Plastic and Reconstructive Surgery. ,vol. 110, pp. 1731- 1744 ,(2002) , 10.1097/01.PRS.0000033936.43357.08
Thomas L Tzikas, Lipografting: autologous fat grafting for total facial rejuvenation. Facial Plastic Surgery. ,vol. 20, pp. 135- 143 ,(2004) , 10.1055/S-2004-861754
U. Veronesi, B. Salvadori, A. Luini, M. Greco, R. Saccozzi, M. del Vecchio, L. Mariani, S. Zurrida, F. Rilke, Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomised trials on 1,973 patients. European Journal of Cancer. ,vol. 31, pp. 1574- 1579 ,(1995) , 10.1016/0959-8049(95)00271-J
Emmanuel Delay, Sebastian Garson, Gilles Tousson, Raphael Sinna, Fat Injection to the Breast: Technique, Results, and Indications Based on 880 Procedures Over 10 Years Aesthetic Surgery Journal. ,vol. 29, pp. 360- 376 ,(2009) , 10.1016/J.ASJ.2009.08.010
Gino Rigotti, Alessandra Marchi, Mirco Gali??, Guido Baroni, Donatella Benati, Mauro Krampera, Annalisa Pasini, Andrea Sbarbati, Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells. Plastic and Reconstructive Surgery. ,vol. 119, pp. 1409- 1422 ,(2007) , 10.1097/01.PRS.0000256047.47909.71
C.W. Chan, S.J. McCulley, R.D. Macmillan, Autologous fat transfer--a review of the literature with a focus on breast cancer surgery. Journal of Plastic Reconstructive and Aesthetic Surgery. ,vol. 61, pp. 1438- 1448 ,(2008) , 10.1016/J.BJPS.2008.08.006
Ali Mojallal, Michel Saint-Cyr, Ignacio Garrido, Autologous fat transfer: Controversies and current indications for breast surgery Journal of Plastic Reconstructive and Aesthetic Surgery. ,vol. 62, pp. 708- 710 ,(2009) , 10.1016/J.BJPS.2009.01.037