Health Impacts of Environmental Mycobacteria

摘要: Environmental mycobacteria are emerging pathogens causing opportunistic infections in humans and animals. The health impacts of human-mycobacterial interactions complex likely much broader than currently recognized. preferentially survive chlorination municipal water, using it as a vector to infect humans. Widespread water has selected more resistant environmental species potentially explains the shift from M. scrofulaceum avium cause cervical lymphadenitis children. Thus, human activities have affected mycobacterial ecology. While slow growth hydrophobicity appear be disadvantages, unique cell wall architecture also grants high biocide antibiotic resistance, while facilitates nutrient acquisition, biofilm formation, spread by aerosolization. remarkable stress tolerance is major reason they pathogens. invade protozoans, exhibiting parasitic symbiotic relationships. molecular mechanisms intracellular pathogenesis animals evolved similar facilitating survival protozoans. In addition outright infection, may play role chronic bowl diseases, allergies, immunity other pulmonary infections, efficacy bacillus Calmette-Guerin vaccination.