Memory enhancement induced by hypothalamic/fornix deep brain stimulation.

作者: Clement Hamani , Mary Pat McAndrews , Melanie Cohn , Michael Oh , Dominik Zumsteg

DOI: 10.1002/ANA.21295

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摘要: Bilateral hypothalamic deep brain stimulation was performed to treat a patient with morbid obesity. We observed, quite unexpectedly, that stimulation evoked detailed autobiographical memories. Associative memory tasks conducted in a double‐blinded “on” versus “off” manner demonstrated that stimulation increased recollection but not familiarity‐based recognition, indicating a functional engagement of the hippocampus. Electroencephalographic source localization showed that hypothalamic deep brain …

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