Calcium binding peptides

作者: Elizabeth Hagerman , Sotirios Tetradis , Fengxia Qi , Randal Eckert , Wenyuan Shi

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摘要: Disclosed herein are a class of compounds comprising peptides the sequence (X-Y-Z)n, wherein X is an amino acid selected from aspartic acid, glutamic asparagine, alanine and glutamine, Y Z acids alanine, serine, threonine, phosphoserine, phosphothreonine, their derivatives. These have property binding tightly specifically to calcified surfaces, making them useful for variety applications including remineralization tooth bone diagnosis defects, treatment analysis presence location deposits both in vitro vivo industrial, synthetic, medical, dental, research where identification, localization, or manipulation calcification desirable.

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