Comparison of the validity of magnetic resonance imaging and positron emission tomography/computed tomography in the preoperative evaluation of patients with uterine corpus cancer

作者: Jeong-Yeol Park , Eyu Nyong Kim , Dae-Yeon Kim , Dae-Shik Suh , Jong-Hyeok Kim

DOI: 10.1016/J.YGYNO.2007.11.044

关键词:

摘要: Abstract Objective. To compare positron emission tomography/computed tomography (PET/CT) with magnetic resonance imaging (MRI) in the preoperative detection of primary lesions and lymph node (LN) distant metastases patients uterine corpus cancer. Methods. The patient cohort consisted 53 women cancer who underwent workup, including both MRI PET/CT scans, surgical staging, pelvic and/or paraaortic LN dissection, between October 2004 June 2007 at Asan Medical Center, Seoul, Korea. Pathologic data from staging were compared results. For area specific analysis, LNs divided into paraaortic, right left areas. Results. In detecting lesions, showed no differences sensitivity (91.5% vs. 89.4%), specificity (33.3% 50.5%), accuracy (84.9% 84.9%), positive predictive value (PPV) 93.3%) negative (NPV) 37.5%). With MRI, sensitivity, specificity, accuracy, PPV NPV for metastatic on area-by-area analysis 46.2%, 87.9%, 83.9%, 28.6% 94.0%, respectively; PET/CT, those 69.2%, 90.3%, 88.3%, 42.9%, 96.6%, respectively. higher but it did not reach statistical significance ( p =0.250). There also NPV. metastasis, 100%, 93.8%, 92.5%, 62.5% Conclusion. cancer, had moderate metastases, indicating that this method cannot replace staging. benefit is its metastases. Because high predicting may have advantages selected are poor candidates

参考文章(19)
Richard L. Wahl, Why nearly all PET of abdominal and pelvic cancers will be performed as PET/CT. The Journal of Nuclear Medicine. ,vol. 45, ,(2004)
OTTO WARBURN, FRANK DICKENS, THE METABOLISM OF TUMORS The American Journal of the Medical Sciences. ,vol. 182, pp. 123- ,(1931) , 10.1097/00000441-193107000-00022
R. SUZUKI, E. MIYAGI, N. TAKAHASHI, A. SUKEGAWA, A. SUZUKI, I. KOIKE, K. SUGIURA, N. OKAMOTO, T. INOUE, F. HIRAHARA, Validity of positron emission tomography using fluoro-2-deoxyglucose for the preoperative evaluation of endometrial cancer. International Journal of Gynecological Cancer. ,vol. 17, pp. 890- 896 ,(2007) , 10.1111/J.1525-1438.2007.00859.X
Chyong-Huey Lai, Tzu-Chen Yen, Ting-Chang Chang, Positron emission tomography imaging for gynecologic malignancy. Current Opinion in Obstetrics & Gynecology. ,vol. 19, pp. 37- 41 ,(2007) , 10.1097/GCO.0B013E32801195C9
Heiko Sch�der, Yusuf E. Erdi, Steven M. Larson, Henry W. D. Yeung, PET/CT: a new imaging technology in nuclear medicine European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 30, pp. 1419- 1437 ,(2003) , 10.1007/S00259-003-1299-6
Tsuneo Saga, Tatsuya Higashi, Takayoshi Ishimori, Marcelo Mamede, Yuji Nakamoto, Takahiro Mukai, Toru Fujita, Kaori Togashi, Shigeo Yura, Toshihiro Higuchi, Masato Kita, Shingo Fujii, Junji Konishi, Clinical value of FDG-PET in the follow up of post-operative patients with endometrial cancer. Annals of Nuclear Medicine. ,vol. 17, pp. 197- 203 ,(2003) , 10.1007/BF02990022
H Hricak, L V Rubinstein, G M Gherman, N Karstaedt, MR imaging evaluation of endometrial carcinoma: results of an NCI cooperative study. Radiology. ,vol. 179, pp. 829- 832 ,(1991) , 10.1148/RADIOLOGY.179.3.2028000
Neil S. Horowitz, Farrokh Dehdashti, Thomas J. Herzog, Janet S. Rader, Matthew A. Powell, Randal K. Gibb, Perry W. Grigsby, Barry A. Siegel, David G. Mutch, Prospective evaluation of FDG-PET for detecting pelvic and para-aortic lymph node metastasis in uterine corpus cancer. Gynecologic Oncology. ,vol. 95, pp. 546- 551 ,(2004) , 10.1016/J.YGYNO.2004.08.009
Masami Futatsubashi, Tatsuo Torizuka, Yasuomi Ouchi, Toshihiko Kanno, Fumitoshi Nakamura, Etsuji Yoshikawa, Makoto Maeda, Munetaka Takekuma, Hiroyuki Okada, Imaging of Gynecologic Tumors: Comparison of 11C-Choline PET with 18F-FDG PET The Journal of Nuclear Medicine. ,vol. 44, pp. 1051- 1056 ,(2003)
Ting-Chang Chang, Koon-Kwan Ng, Swei Hsueh, Huei-Jean Huang, Hung-Hsueh Chou, Chien-Sheng Tsai, Tzu-Chen Yen, Tzu-I Wu, Chyong-Huey Lai, Angel Chao, 18F-FDG PET in the management of endometrial cancer. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 33, pp. 36- 44 ,(2006) , 10.1007/S00259-005-1876-Y