Thermoplastic fluoropolymer-coated medical devices

摘要: A medical device provided with at least a partial surface coating of thermoplastic copolymer tetrafluoroethylene and perfluoroalkylvinylether that is free cross-linking monomers curing agents. The fluoropolymer preferably an amorphous thermoplastic, highly inert biocompatible, has elastomeric characteristics provide desirable mechanical properties such as good flexibility durability. These allow the to be considered “functionally transparent” because it withstands deformations required for assembly, deployment, expansion, placement devices, without any adverse effect on biological functionality coated device. Further, its inertness, derived from perfluorocarbon structure, contributes functionally transparent nature. can various liquid or solid additives, loaded large quantities additives including wide range therapeutic agents, excellent drug elution when elutable are used. surprising given absence agents would otherwise render materials inadequately biocompatible. may perfluoromethylvinylether, perfluoroethylvinylether perfluoropropylvinylether.