Targeting renal cell carcinoma with a HIF-2 antagonist

作者: Alana Christie , Min Soo Kim , Eboni Holloman , Andrea Pavia-Jimenez , Farrah Homayoun

DOI: 10.1038/NATURE19796

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摘要: Clear cell renal cell carcinoma (ccRCC) is characterized by inactivation of the von Hippel-Lindau tumour suppressor gene (VHL) 1 , 2 . Because no other gene is mutated as frequently …

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