摘要: The initiation of transcription is the most important step for gene regulation in eubacteria. To initiate transcription, RNA polymerase has to associate with a small protein, known as σ-factor. σ-factor directs specific class promoter sequences. Most bacterial species synthesize several different σ-factors that recognize consensus This variety provides bacteria opportunity maintain basal expression well response altered environmental or developmental signals. review focuses on function, and distribution 14 classes are presently known.